top of page
  • Facebook
  • Twitter
  • LinkedIn

Nano-mechanics Lab

The Nano-mechanics group at IISER Pune was started in 2008 with a philosophy of development of novel techniques to understand molecular level processes in variety of areas. The group has developed novel instruments in the field of single molecule force spectroscopy and correlation spectroscopy.

Research Projects

Nano-mechanics lab is an interdisciplinary research group having a strong emphasis on development of novel force microscopic tools to investigate mechanics at mesoscopic scale. The lab has following projects and needs people from diverse backgrounds such as mechanical and electronics engineering to basic science disciplines such as Physics, Biology and Chemistry. Interested people (Engineers and researchers) are encouraged to send an e-mail with their CV to following e-mail address: s.patil@iiserpune.ac.in

Team

May the force be with you...

​

WhatsApp Image 2023-05-23 at 6.56.40 PM.jpeg

Shivprasad Patil

Professor, Wellcome-DBT Intermediate fellow

1995 B.Sc. Willingdon College, Shivaji University

1996 M.Sc. University of Pune

2003 Ph.D. University of Pune

2003-2005 Post-doctoral Fellow at Wayne State University, USA

2005-2007 Post-doctoral Fellow at IMM, CSIC Madrid, Spain

  • Facebook
  • Twitter
  • LinkedIn

PhD Scholars

​

​

20240817_141850.jpg

Shrikrishna Bhagwat

​

Instrumentation (AFM) and studying Mechanical Behaviors of Proteins 

WhatsApp Image 2025-03-25 at 11.03_edite

Vedant Gaonkar

​

Works on instrumentation and single- molecule experiments.

​

Apart from research you can find me on badminton court. 

​

20210807012903_IMG_0305 (1).JPG

Shubham Padhi

​

Study the mechanical properties of cells under different physiological conditions.

​

Also interested in Philosophy, music, badminton, and cricket.

WhatsApp Image 2025-03-22 at 12.48.27 PM.jpeg

Manmath Sahoo

​

Works on instrumentation and design, and protein pulling experiments. 

​

Also involved in geopolitical arguments, trekking, 

WhatsApp Image 2025-03-22 at 12.38.57 PM.jpeg

Harsh Rathore

​

​Works on Finite element simulation and data analysis.

​

Keeps interest in Photography, chess, and athletic activities.

Aman.jpg

Aman Tumbal

​

​Stress Strain analysis of cells 

​

Also interested in trekking and casual gaming

R.jpg

Sanskruti Nalawade

​

Mechanical characterization of cells under different physiological conditions

​

Alumini

surya.jpg

S.P.S Deopa

Postdoctral Fellow at JILA

  • Facebook
  • Twitter
  • LinkedIn
aman.jpg

Amandeep

Application Scientist at Bruker nano surface & Metrology

  • Facebook
  • Twitter
  • LinkedIn
shatru.jpg

Shatruhan Singh Rajput

Postdoctoral Research Fellow at MGH, Harvard Medical School

  • Facebook
  • Twitter
  • LinkedIn
ajith.jpg

Ajith V. J.

Postdoctral Fellow at University of Texas,Austin

  • Facebook
  • Twitter
  • LinkedIn
vikhyat.jpg

Vikhyaat Ahlawat

Postdoctral Research Fellow at University of Illinois Chicago

​

  • Facebook
  • Twitter
  • LinkedIn
saurabh.jpg

Saurabh Talele

PhD student at Ulsan National Institute of science and technology

123-456-7890

  • Facebook
  • Twitter
  • LinkedIn
pdf1_edited.jpg

Arpita Roychoudhury

Researcher at

Université de Liège

  • Facebook
  • Twitter
  • LinkedIn
monica.jpg

Monica Raina

DST Research Scientist DST Research Scientist

Cochin University of Science and Technology

​

  • Facebook
  • Twitter
  • LinkedIn
phd1.jpg

A. V. R. Murthy

INSPIRE Faculty at DIAT Pune

​

  • Facebook
  • Twitter
  • LinkedIn
roshani.jpg

Roshni Bano

Ph.D at University of Illonois, Urbana Champaign, USA.

​

  • Facebook
  • Twitter
  • LinkedIn
al1.jpg

Vibham Shukla

Currently works for Heymath, Chennai.

​

  • Facebook
  • Twitter
  • LinkedIn
pr1.jpg

Vinod Kanawade

​Currently working for GE, Banglore

​

  • Facebook
  • Twitter
  • LinkedIn
Pf1.jpg

Javed Ahmad

​M.Tech at CSIO,Mohali.

​

  • Facebook
  • Twitter
  • LinkedIn

Latest Publications

Pathogenic Huntingtin aggregates alter actin organization and cellular stiffness resulting in stalled clathrin- mediated endocytosis

Aggregation of mutant forms of Huntingtin is the underlying feature of neurodegeneration observed in Huntington’s disorder. In addition to neurons, cellular processes in non- neuronal cell types are also shown to be affected. Cells expressing neurodegeneration–associated mutant proteins show altered uptake of ligands, suggestive of impaired endocytosis, in a manner as yet unknown. Using live cell imaging, we show that clathrin- mediated endocytosis (CME) is affected in Drosophila hemocytes and mammalian cells containing Huntingtin aggregates. This is also accompanied by alterations in the organization of the actin cytoskeleton resulting in increased cellular stiffness. 

​

Nano-mechanics Lab
H-cross (lab no:220)
IISER Pune Campus
Pashan, Pune-411008
Maharashtra, India

+91 (20) 2590 8104

​

bottom of page